Kymathera grabs $80M series B for next-gen PI3Kα inhibitor

·20h ago
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Kymathera added $80 million in a series B round to advance its PI3Kα inhibitor K-1728 into clinical development. The next-generation drug has better selectivity for mutant PI3Kα over wild-type protein compared to current PI3Kα inhibitors, increasing the therapeutic window and potentially making K-1728 more potent with less hyperglycemia.

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Bioworld

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